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KMID : 0043319840070020137
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Archives of Pharmacal Research
1984 Volume.7 No. 2 p.137 ~ p.139
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The Molecular Sturcture of (+)-6-Methxt-alpha-methyl-2-naphthaleneacetic Acid Determined by X-Ray Method
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Kim YB
Song HJ
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Abstract
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The molecular structure of (+)-6-Methoxy-alpha-methyl-2-naphthaleneacetic acid(Naproxen), C14H14O3, was determined by X-Ray diffraction technique. Naproxen crystallized in P21 with two molecules in the unit cell of dimensions a = 7.855, b = 5.783, C = 13.347angstrom and beta=93.9o. The structure was solved with the SHELX program system. The present R value is 0.099. The molecules are connected by the intermolecular OH...O hydrogen bonds.
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KEYWORD
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